Testosterone antagonizes paraquat-induced cardiomyocyte senescence via the mIGF-1/SIRT1 signaling pathway

Testosterone has been demonstrated to antagonize doxorubicin-induced cardiomyocyte senescence. However, whether testosterone prevents the paraquat-induced cardiomyocyte senescence is largely unknown. The detection of SA-β-gal activity was performed using senescence β-gal staining kit and the reactiv...

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Detalles Bibliográficos
Autores principales: Yu, Xing, Zheng, Jianyi, Cai, Tengfei, Wang, Zhijian, Zhu, Guiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485312/
https://www.ncbi.nlm.nih.gov/pubmed/32901689
http://dx.doi.org/10.1590/1414-431X20209849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485312/
https://www.ncbi.nlm.nih.gov/pubmed/32901689
http://dx.doi.org/10.1590/1414-431X20209849

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