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Constant Levels of Tau Phosphorylation in the Brain of htau Mice

Excessive tau phosphorylation is the hallmark of tauopathies. Today’s research thus focusses on the development of drugs targeting this pathological feature. To test new drugs in preclinical studies, animal models are needed that properly mimic this pathological hallmark. The htau mouse is a well-kn...

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Detalles Bibliográficos
Autores principales: Neddens, Joerg, Daurer, Magdalena, Loeffler, Tina, Alzola Aldamizetxebarria, Saioa, Flunkert, Stefanie, Hutter-Paier, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485327/
https://www.ncbi.nlm.nih.gov/pubmed/32982685
http://dx.doi.org/10.3389/fnmol.2020.00136