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Intrathecally Administered Apelin-13 Alleviated Complete Freund’s Adjuvant-Induced Inflammatory Pain in Mice

Apelin is the endogenous ligand for APJ, a G-protein-coupled receptor. Apelin gene and protein are widely distributed in the central nervous system and peripheral tissues. The role of apelin in chronic inflammatory pain is still unclear. In the present study, a mouse model of complete Freund’s adjuv...

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Detalles Bibliográficos
Autores principales: Lv, Shuangyu, Zhang, Xiaomei, Zhou, Yuchen, Feng, Yu, Yang, Yanjie, Wang, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485460/
https://www.ncbi.nlm.nih.gov/pubmed/32982745
http://dx.doi.org/10.3389/fphar.2020.01335