Cantharidin Induces Apoptosis and Promotes Differentiation of AML Cells Through Nuclear Receptor Nur77-Mediated Signaling Pathway

BACKGROUND: Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by uncontrolled proliferation and accumulation of myeloblasts in the bone marrow (BM), blood, and other organs. The nuclear receptors Nur77 is a common feature in leukemic blasts and has emerged as a key therapeutic...

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Detalles Bibliográficos
Autores principales: Yu, Zanyang, Li, Li, Wang, Chengqiang, He, Hui, Liu, Gen, Ma, Haoyue, Pang, Lei, Jiang, Mingdong, Lu, Qianwei, Li, Pan, Qi, Hongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485522/
https://www.ncbi.nlm.nih.gov/pubmed/32982739
http://dx.doi.org/10.3389/fphar.2020.01321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485522/
https://www.ncbi.nlm.nih.gov/pubmed/32982739
http://dx.doi.org/10.3389/fphar.2020.01321

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