Role of Glucuronidation Pathway in Quetiapine Metabolism: An In vivo Drug–Drug Interaction Study between Quetiapine and Probenecid

BACKGROUND: Uridine 5'-diphospho-glucuronosyltransferase (UGT) enzymes play a significant role in the metabolism of quetiapine, and coadministration with a UGT inhibitor/inducer drug may change its pharmacokinetic profile. OBJECTIVE: The objective of this study was to assess the impact of probe...

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Detalles Bibliográficos
Autores principales: Sattar, Haseeb, Jadoon, Sarmad Sheraz, Yang, Ni, Li, Shihong, Xu, Mingzhen, Han, Yong, Ramzan, Adil, Li, Weiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485652/
https://www.ncbi.nlm.nih.gov/pubmed/32952511
http://dx.doi.org/10.4103/sjmms.sjmms_441_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485652/
https://www.ncbi.nlm.nih.gov/pubmed/32952511
http://dx.doi.org/10.4103/sjmms.sjmms_441_19

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