Cargando…

Targeting of interleukin-10 receptor by a potential human interleukin-10 peptide efficiently blocks interleukin-10 pathway-dependent cell proliferation

OBJECTIVE: Human interleukin-10 (IL-10) is a dimeric and pleiotropic cytokine that plays a crucial role in cellular immunoregulatory responses. As IL-10 binds to its receptors, IL-10Ra and IL-10Rb, it will suppress or induce the downstream cellular immune responses to protect from diseases. MATERIAL...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Chun-Chun, Liu, Cheng-Der, Pan, Sheng-Feng, Huang, Wei-Han, Peng, Chih-Wen, Hsu, Hao-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485672/
https://www.ncbi.nlm.nih.gov/pubmed/32955521
http://dx.doi.org/10.4103/tcmj.tcmj_237_19