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Targeting of interleukin-10 receptor by a potential human interleukin-10 peptide efficiently blocks interleukin-10 pathway-dependent cell proliferation
OBJECTIVE: Human interleukin-10 (IL-10) is a dimeric and pleiotropic cytokine that plays a crucial role in cellular immunoregulatory responses. As IL-10 binds to its receptors, IL-10Ra and IL-10Rb, it will suppress or induce the downstream cellular immune responses to protect from diseases. MATERIAL...
Autores principales: | Chang, Chun-Chun, Liu, Cheng-Der, Pan, Sheng-Feng, Huang, Wei-Han, Peng, Chih-Wen, Hsu, Hao-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485672/ https://www.ncbi.nlm.nih.gov/pubmed/32955521 http://dx.doi.org/10.4103/tcmj.tcmj_237_19 |
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