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CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis

CTCF is overexpressed in several cancers and plays crucial roles in regulating aggressiveness, but little is known about whether CTCF drives colorectal cancer progression. Here, we identified a tumor-promoting role for CTCF in colorectal cancer. Our study demonstrated that CTCF was upregulated in co...

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Detalles Bibliográficos
Autores principales: Lai, Qiuhua, Li, Qingyuan, He, Chengcheng, Fang, Yuxin, Lin, Simin, Cai, Jianqun, Ding, Jian, Zhong, Qian, Zhang, Yue, Wu, Changjie, Wang, Xinke, He, Juan, Liu, Yongfeng, Yan, Qun, Li, Aimin, Liu, Side
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485712/
https://www.ncbi.nlm.nih.gov/pubmed/32688344
http://dx.doi.org/10.18632/aging.103648