Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing

Antibody therapeutics are one of the most important classes of drugs. Antibody structures have become an integral part of predicting the behavior of potential therapeutics, either directly or as the basis of modeling. Structures of Fab:antigen complexes have even greater value. While the crystalliza...

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Detalles Bibliográficos
Autores principales: Lieu, Ricky, Antonysamy, Stephen, Druzina, Zhanna, Ho, Carolyn, Kang, N. Rebecca, Pustilnik, Anna, Wang, Jing, Atwell, Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485759/
https://www.ncbi.nlm.nih.gov/pubmed/32915778
http://dx.doi.org/10.1371/journal.pone.0232311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485759/
https://www.ncbi.nlm.nih.gov/pubmed/32915778
http://dx.doi.org/10.1371/journal.pone.0232311

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