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Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing
Antibody therapeutics are one of the most important classes of drugs. Antibody structures have become an integral part of predicting the behavior of potential therapeutics, either directly or as the basis of modeling. Structures of Fab:antigen complexes have even greater value. While the crystalliza...
Autores principales: | Lieu, Ricky, Antonysamy, Stephen, Druzina, Zhanna, Ho, Carolyn, Kang, N. Rebecca, Pustilnik, Anna, Wang, Jing, Atwell, Shane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485759/ https://www.ncbi.nlm.nih.gov/pubmed/32915778 http://dx.doi.org/10.1371/journal.pone.0232311 |
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