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Zinc oxide nanoparticles modulate the gene expression of ZnT(1) and ZIP(8) to manipulate zinc homeostasis and stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells

Zinc ions (Zn(2+)) are important messenger molecules involved in various physiological functions. To maintain the homeostasis of cytosolic Zn(2+) concentration ([Zn(2+)](c)), Zrt/Irt-related proteins (ZIPs) and Zn(2+) transporters (ZnTs) are the two families of proteins responsible for decreasing an...

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Detalles Bibliográficos
Autores principales: Pan, Chien-Yuan, Lin, Fang-Yu, Kao, Lung-Sen, Huang, Chien-Chang, Liu, Pei-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485861/
https://www.ncbi.nlm.nih.gov/pubmed/32915786
http://dx.doi.org/10.1371/journal.pone.0232729