Population and Noncompartmental Pharmacokinetics of Sodium Oxybate Support Weight‐Based Dosing in Children and Adolescents With Narcolepsy With Cataplexy

The pharmacokinetics (PKs) of sodium oxybate (SXB) was evaluated in a subset of participants from a study of SXB treatment in children (aged 7–11 years; n = 11) and adolescents (aged 12–17 years; n = 18) with narcolepsy with cataplexy. PK evaluation was conducted over 2 nights during the period when...

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Detalles Bibliográficos
Autores principales: Chen, Cuiping, Rosen, Carol L., Ruoff, Chad, Boyce, Leslie H., Parvataneni, Rupa, Zomorodi, Katie, Brantley, Scott, Sale, Mark, Plazzi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485950/
https://www.ncbi.nlm.nih.gov/pubmed/32216084
http://dx.doi.org/10.1111/cts.12780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485950/
https://www.ncbi.nlm.nih.gov/pubmed/32216084
http://dx.doi.org/10.1111/cts.12780

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