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Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin‐Induced Cutaneous Adverse Drug Reactions

The role of cytochrome P450 (CYP)2C9 and CYP2C19 genetic variation in risk for phenytoin‐induced cutaneous adverse drug events is not well understood independently of the human leukocyte antigen B (HLA‐B)*15:02 risk allele. In the multi‐ethnic resource for Genetic Epidemiology Research on Adult Heal...

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Detalles Bibliográficos
Autores principales: Fohner, Alison E., Rettie, Allan E., Thai, Khanh K., Ranatunga, Dilrini K., Lawson, Brian L., Liu, Vincent X., Schaefer, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485959/
https://www.ncbi.nlm.nih.gov/pubmed/32216088
http://dx.doi.org/10.1111/cts.12787