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Building the vertebrate codex using the gene breaking protein trap library

One key bottleneck in understanding the human genome is the relative under-characterization of 90% of protein coding regions. We report a collection of 1200 transgenic zebrafish strains made with the gene-break transposon (GBT) protein trap to simultaneously report and reversibly knockdown the tagge...

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Detalles Bibliográficos
Autores principales: Ichino, Noriko, Serres, MaKayla R, Urban, Rhianna M, Urban, Mark D, Treichel, Anthony J, Schaefbauer, Kyle J, Tallant, Lauren E, Varshney, Gaurav K, Skuster, Kimberly J, McNulty, Melissa S, Daby, Camden L, Wang, Ying, Liao, Hsin-kai, El-Rass, Suzan, Ding, Yonghe, Liu, Weibin, Anderson, Jennifer L, Wishman, Mark D, Sabharwal, Ankit, Schimmenti, Lisa A, Sivasubbu, Sridhar, Balciunas, Darius, Hammerschmidt, Matthias, Farber, Steven Arthur, Wen, Xiao-Yan, Xu, Xiaolei, McGrail, Maura, Essner, Jeffrey J, Burgess, Shawn M, Clark, Karl J, Ekker, Stephen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486118/
https://www.ncbi.nlm.nih.gov/pubmed/32779569
http://dx.doi.org/10.7554/eLife.54572