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EDF1 coordinates cellular responses to ribosome collisions

Translation of aberrant mRNAs induces ribosomal collisions, thereby triggering pathways for mRNA and nascent peptide degradation and ribosomal rescue. Here we use sucrose gradient fractionation combined with quantitative proteomics to systematically identify proteins associated with collided ribosom...

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Detalles Bibliográficos
Autores principales: Sinha, Niladri K, Ordureau, Alban, Best, Katharina, Saba, James A, Zinshteyn, Boris, Sundaramoorthy, Elayanambi, Fulzele, Amit, Garshott, Danielle M, Denk, Timo, Thoms, Matthias, Paulo, Joao A, Harper, J Wade, Bennett, Eric J, Beckmann, Roland, Green, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486125/
https://www.ncbi.nlm.nih.gov/pubmed/32744497
http://dx.doi.org/10.7554/eLife.58828