Cargando…

EDF1 coordinates cellular responses to ribosome collisions

Translation of aberrant mRNAs induces ribosomal collisions, thereby triggering pathways for mRNA and nascent peptide degradation and ribosomal rescue. Here we use sucrose gradient fractionation combined with quantitative proteomics to systematically identify proteins associated with collided ribosom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sinha, Niladri K, Ordureau, Alban, Best, Katharina, Saba, James A, Zinshteyn, Boris, Sundaramoorthy, Elayanambi, Fulzele, Amit, Garshott, Danielle M, Denk, Timo, Thoms, Matthias, Paulo, Joao A, Harper, J Wade, Bennett, Eric J, Beckmann, Roland, Green, Rachel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486125/ https://www.ncbi.nlm.nih.gov/pubmed/32744497 http://dx.doi.org/10.7554/eLife.58828

Ejemplares similares

Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized
por: Garshott, Danielle M, et al.
Publicado: (2020)

Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection
por: Sundaramoorthy, Elayanambi, et al.
Publicado: (2021)

The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding
por: Kudva, Renuka, et al.
Publicado: (2018)

Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase
por: Mitterer, Valentin, et al.
Publicado: (2023)

Structural and mutational analysis of the ribosome-arresting human XBP1u
por: Shanmuganathan, Vivekanandan, et al.
Publicado: (2019)

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae
por: Heuer, André, et al.
Publicado: (2017)

Systematic Quantitative Analysis of Ribosome Inventory Upon Nutrient Stress
por: An, Heeseon, et al.
Publicado: (2020)

Visualizing formation of the active site in the mitochondrial ribosome
por: Chandrasekaran, Viswanathan, et al.
Publicado: (2021)

Puromycin reactivity does not accurately localize translation at the subcellular level
por: Enam, Syed Usman, et al.
Publicado: (2020)

Structure of RNA polymerase bound to ribosomal 30S subunit
por: Demo, Gabriel, et al.
Publicado: (2017)

Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness
por: Tye, Blake W, et al.
Publicado: (2019)

Gradual compaction of the nascent peptide during cotranslational folding on the ribosome
por: Liutkute, Marija, et al.
Publicado: (2020)

Ribosome surface properties may impose limits on the nature of the cytoplasmic proteome
por: Schavemaker, Paul E, et al.
Publicado: (2017)

Dynamics of ribosomes and release factors during translation termination in E. coli
por: Adio, Sarah, et al.
Publicado: (2018)

Conformational switches control early maturation of the eukaryotic small ribosomal subunit
por: Hunziker, Mirjam, et al.
Publicado: (2019)

Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription
por: Stumper, Sarah K, et al.
Publicado: (2019)

Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
por: Hobson, Benjamin D, et al.
Publicado: (2020)

Alkylative damage of mRNA leads to ribosome stalling and rescue by trans translation in bacteria
por: Thomas, Erica N, et al.
Publicado: (2020)

A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution
por: Mohammad, Fuad, et al.
Publicado: (2019)

Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
por: Eapen, Vinay V, et al.
Publicado: (2021)

The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers
por: Klingauf-Nerurkar, Purnima, et al.
Publicado: (2020)

Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
por: Dennerlein, Sven, et al.
Publicado: (2021)

Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress
por: Crawford, Robert A, et al.
Publicado: (2022)

Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC
por: Yoshikawa, Harunori, et al.
Publicado: (2018)

Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36
por: van den Heuvel, Jasmin, et al.
Publicado: (2021)

Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes
por: Juette, Manuel F, et al.
Publicado: (2022)

LARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protection
por: Mattijssen, Sandy, et al.
Publicado: (2017)

The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling
por: Su, Ting, et al.
Publicado: (2017)

Prefabrication of a ribosomal protein subcomplex essential for eukaryotic ribosome formation
por: Peña, Cohue, et al.
Publicado: (2016)

Signature betwens CERN and EDF
por: Brice, Maximilien
Publicado: (2015)

A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly
por: Schütz, Sabina, et al.
Publicado: (2014)

The supply of the 148 MW CERN accelerator pulsed load by the EDF II Repercussions on the EDF EHV system
por: Gaborit, J C, et al.
Publicado: (1974)

Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
por: Nowinski, Sara M, et al.
Publicado: (2020)

TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
por: Xu, Simiao, et al.
Publicado: (2021)

Direct measurement of the mechanical work during translocation by the ribosome
por: Liu, Tingting, et al.
Publicado: (2014)

Ribosomes slide on lysine-encoding homopolymeric A stretches
por: Koutmou, Kristin S, et al.
Publicado: (2015)

Mechanism of ribosome rescue by ArfA and RF2
por: Demo, Gabriel, et al.
Publicado: (2017)

The elemental mechanism of transcriptional pausing
por: Saba, Jason, et al.
Publicado: (2019)

The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation
por: Yonashiro, Ryo, et al.
Publicado: (2016)

NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA
por: Mandell, Zachary F, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v5m11ru7aig94paf12m2cn6at6