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Potential Therapeutic Roles for Direct Factor Xa Inhibitors in Coronavirus Infections

Human factor Xa (FXa) is a serine protease of the common coagulation pathway. FXa is known to activate prothrombin to thrombin, which eventually leads to the formation of cross-linked blood clots. While this process is important in maintaining hemostasis, excessive thrombin generation results in a h...

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Detalles Bibliográficos
Autor principal: Al-Horani, Rami A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486161/
https://www.ncbi.nlm.nih.gov/pubmed/32918208
http://dx.doi.org/10.1007/s40256-020-00438-6