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Potential Therapeutic Roles for Direct Factor Xa Inhibitors in Coronavirus Infections
Human factor Xa (FXa) is a serine protease of the common coagulation pathway. FXa is known to activate prothrombin to thrombin, which eventually leads to the formation of cross-linked blood clots. While this process is important in maintaining hemostasis, excessive thrombin generation results in a h...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486161/ https://www.ncbi.nlm.nih.gov/pubmed/32918208 http://dx.doi.org/10.1007/s40256-020-00438-6 |