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Single-Cell Mechanical Analysis of Human Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Testing and Pathophysiological Studies

Current platforms for studying the mechanical properties of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) as single cells do not measure forces directly, require numerous assumptions, and cannot study cell mechanics at different loading conditions. We present a method for directly me...

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Detalles Bibliográficos
Autores principales: Ballan, Nimer, Shaheen, Naim, Keller, Gordon M., Gepstein, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486198/
https://www.ncbi.nlm.nih.gov/pubmed/32763158
http://dx.doi.org/10.1016/j.stemcr.2020.07.006