Cargando…
Single-Cell Mechanical Analysis of Human Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Testing and Pathophysiological Studies
Current platforms for studying the mechanical properties of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) as single cells do not measure forces directly, require numerous assumptions, and cannot study cell mechanics at different loading conditions. We present a method for directly me...
Autores principales: | Ballan, Nimer, Shaheen, Naim, Keller, Gordon M., Gepstein, Lior |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486198/ https://www.ncbi.nlm.nih.gov/pubmed/32763158 http://dx.doi.org/10.1016/j.stemcr.2020.07.006 |
Ejemplares similares
-
Reply to ‘Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?’
por: Shiti, Assad, et al.
Publicado: (2021) -
Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
por: Goldfracht, Idit, et al.
Publicado: (2020) -
Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters
por: Shinnawi, Rami, et al.
Publicado: (2015) -
Calcium Handling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
por: Itzhaki, Ilanit, et al.
Publicado: (2011) -
Utilizing human induced pluripotent stem cells to study atrial arrhythmias in the short QT syndrome
por: Shiti, Assad, et al.
Publicado: (2023)