“Reprogram Enablement” as an Assay for Identifying Early Oncogenic Pathways by Their Ability to Allow Neoplastic Cells to Reacquire an Epiblast State

One approach to understanding how tissue-specific cancers emerge is to determine the requirements for “reprograming” such neoplastic cells back to their developmentally normal primordial pre-malignant epiblast-like pluripotent state and then scrutinizing their spontaneous reconversion to a neoplasm,...

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Detalles Bibliográficos
Autores principales: Kong, Yanjun, Gimple, Ryan C., McVicar, Rachael N., Hodges, Andrew P., Yin, Jun, Liu, Yang, Zhan, Weiwei, Snyder, Evan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486218/
https://www.ncbi.nlm.nih.gov/pubmed/32795421
http://dx.doi.org/10.1016/j.stemcr.2020.07.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486218/
https://www.ncbi.nlm.nih.gov/pubmed/32795421
http://dx.doi.org/10.1016/j.stemcr.2020.07.016

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