Mitochondrial ubiquinol oxidation is necessary for tumor growth

The mitochondrial electron transport chain (ETC) is necessary for tumor growth(1–6) and its inhibition has demonstrated efficacy in combination with immuno-, antiangiogenic, or oncogene targeted-therapies(7–9). Furthermore, brain and lung human tumors display robust glucose oxidation by mitochondria...

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Detalles Bibliográficos
Autores principales: Martínez-Reyes, Inmaculada, Robles Cardona, Luzivette, Kong, Hyewon, Vasan, Karthik, McElroy, Gregory S., Werner, Marie, Kihshen, Hermon, Reczek, Colleen R., Weinberg, Samuel E., Gao, Peng, Steinert, Elizabeth M., Piseaux, Raul, Budinger, G.R. Scott, Chandel, Navdeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486261/
https://www.ncbi.nlm.nih.gov/pubmed/32641834
http://dx.doi.org/10.1038/s41586-020-2475-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486261/
https://www.ncbi.nlm.nih.gov/pubmed/32641834
http://dx.doi.org/10.1038/s41586-020-2475-6

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