Elucidating the role of metal ions in carbonic anhydrase catalysis

Why metalloenzymes often show dramatic changes in their catalytic activity when subjected to chemically similar but non-native metal substitutions is a long-standing puzzle. Here, we report on the catalytic roles of metal ions in a model metalloenzyme system, human carbonic anhydrase II (CA II). Thr...

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Detalles Bibliográficos
Autores principales: Kim, Jin Kyun, Lee, Cheol, Lim, Seon Woo, Adhikari, Aniruddha, Andring, Jacob T., McKenna, Robert, Ghim, Cheol-Min, Kim, Chae Un
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486293/
https://www.ncbi.nlm.nih.gov/pubmed/32917908
http://dx.doi.org/10.1038/s41467-020-18425-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486293/
https://www.ncbi.nlm.nih.gov/pubmed/32917908
http://dx.doi.org/10.1038/s41467-020-18425-5

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