Soft Matrix Promotes Cardiac Reprogramming via Inhibition of YAP/TAZ and Suppression of Fibroblast Signatures

Direct cardiac reprogramming holds great potential for regenerative medicine. However, it remains inefficient, and induced cardiomyocytes (iCMs) generated in vitro are less mature than those in vivo, suggesting that undefined extrinsic factors may regulate cardiac reprogramming. Previous in vitro st...

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Detalles Bibliográficos
Autores principales: Kurotsu, Shota, Sadahiro, Taketaro, Fujita, Ryo, Tani, Hidenori, Yamakawa, Hiroyuki, Tamura, Fumiya, Isomi, Mari, Kojima, Hidenori, Yamada, Yu, Abe, Yuto, Murakata, Yoshiko, Akiyama, Tatsuya, Muraoka, Naoto, Harada, Ichiro, Suzuki, Takeshi, Fukuda, Keiichi, Ieda, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486305/
https://www.ncbi.nlm.nih.gov/pubmed/32857980
http://dx.doi.org/10.1016/j.stemcr.2020.07.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486305/
https://www.ncbi.nlm.nih.gov/pubmed/32857980
http://dx.doi.org/10.1016/j.stemcr.2020.07.022

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