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Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway

We explored how tabersonine (Tab) protected against dexamethasone (Dex)-induced osteoporosis. Osteoblasts were treated with Dex (100 µM) with or without Table (5 or 10 µM). We measured cell viability, alkaline phosphatase (ALP) activity, and mitochondrial superoxide and reactive oxygen species level...

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Detalles Bibliográficos
Autores principales: Sun, Xi, Gan, Lijun, Li, Nan, Sun, Shuyi, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486361/
https://www.ncbi.nlm.nih.gov/pubmed/32915329
http://dx.doi.org/10.1186/s13568-020-01098-0