Hyperacetylated chromatin domains mark cell type-specific genes and suggest distinct modes of enhancer function

Stratification of enhancers by signal strength in ChIP-seq assays has resulted in the establishment of super-enhancers as a widespread and useful tool for identifying cell type-specific, highly expressed genes and associated pathways. We examine a distinct method of stratification that focuses on pe...

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Detalles Bibliográficos
Autores principales: Fox, Sierra, Myers, Jacquelyn A., Davidson, Christina, Getman, Michael, Kingsley, Paul D., Frankiewicz, Nicholas, Bulger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486385/
https://www.ncbi.nlm.nih.gov/pubmed/32917861
http://dx.doi.org/10.1038/s41467-020-18303-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486385/
https://www.ncbi.nlm.nih.gov/pubmed/32917861
http://dx.doi.org/10.1038/s41467-020-18303-0

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