Selective inhibition of CBP/p300 HAT by A-485 results in suppression of lipogenesis and hepatic gluconeogenesis

The histone acetyltransferases CREB-binding protein (CBP) and its paralogue p300 are transcriptional coactivators which are essential for a multitude of signaling pathways and energy homeostasis. However, the role of CBP/p300 HAT domain in regulating energy balance is still unclear. Here, C57BL/6 mi...

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Detalles Bibliográficos
Autores principales: Zhou, Feiye, Liu, Qianqian, Zhang, Linlin, Zhu, Qin, Wang, Shushu, Zhu, Kecheng, Deng, Ruyuan, Liu, Yun, Yuan, Guoyue, Wang, Xiao, Zhou, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486386/
https://www.ncbi.nlm.nih.gov/pubmed/32917859
http://dx.doi.org/10.1038/s41419-020-02960-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486386/
https://www.ncbi.nlm.nih.gov/pubmed/32917859
http://dx.doi.org/10.1038/s41419-020-02960-6

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