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Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

Arterial macrophages have different developmental origins, but the association of macrophage ontogeny with their phenotypes and functions in adulthood is still unclear. Here, we combine macrophage fate-mapping analysis with single-cell RNA sequencing to establish their cellular identity during homeo...

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Detalles Bibliográficos
Autores principales: Weinberger, Tobias, Esfandyari, Dena, Messerer, Denise, Percin, Gulce, Schleifer, Christian, Thaler, Raffael, Liu, Lulu, Stremmel, Christopher, Schneider, Vanessa, Vagnozzi, Ronald J., Schwanenkamp, Jennifer, Fischer, Maximilian, Busch, Katrin, Klapproth, Kay, Ishikawa-Ankerhold, Hellen, Klösges, Lukas, Titova, Anna, Molkentin, Jeffery D., Kobayashi, Yasuhiro, Engelhardt, Stefan, Massberg, Steffen, Waskow, Claudia, Perdiguero, Elisa Gomez, Schulz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486394/
https://www.ncbi.nlm.nih.gov/pubmed/32917889
http://dx.doi.org/10.1038/s41467-020-18287-x