Cargando…

Allosteric coupling between α-rings of the 20S proteasome

Proteasomal machinery performs essential regulated protein degradation in eukaryotes. Classic proteasomes are symmetric, with a regulatory ATPase docked at each end of the cylindrical 20S. Asymmetric complexes are also present in cells, either with a single ATPase or with an ATPase and non-ATPase at...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Zanlin, Yu, Yadong, Wang, Feng, Myasnikov, Alexander G., Coffino, Philip, Cheng, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486400/
https://www.ncbi.nlm.nih.gov/pubmed/32917864
http://dx.doi.org/10.1038/s41467-020-18415-7