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Allosteric coupling between α-rings of the 20S proteasome
Proteasomal machinery performs essential regulated protein degradation in eukaryotes. Classic proteasomes are symmetric, with a regulatory ATPase docked at each end of the cylindrical 20S. Asymmetric complexes are also present in cells, either with a single ATPase or with an ATPase and non-ATPase at...
Autores principales: | Yu, Zanlin, Yu, Yadong, Wang, Feng, Myasnikov, Alexander G., Coffino, Philip, Cheng, Yifan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486400/ https://www.ncbi.nlm.nih.gov/pubmed/32917864 http://dx.doi.org/10.1038/s41467-020-18415-7 |
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