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SOX1 Is Required for the Specification of Rostral Hindbrain Neural Progenitor Cells from Human Embryonic Stem Cells

Region-specific neural progenitor cells (NPCs) can be generated from human embryonic stem cells (hESCs) by modulating signaling pathways. However, how intrinsic transcriptional factors contribute to the neural regionalization is not well characterized. Here, we generate region-specific NPCs from hES...

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Detalles Bibliográficos
Autores principales: Liu, Xinyuan, Fang, Zhuoqing, Wen, Jing, Tang, Fan, Liao, Bing, Jing, Naihe, Lai, Dongmei, Jin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486433/
https://www.ncbi.nlm.nih.gov/pubmed/32905879
http://dx.doi.org/10.1016/j.isci.2020.101475