Polyglutamine-containing microglia leads to disturbed differentiation and neurite retraction of neuron-like cells

Expanded polyglutamine-containing proteins in neurons intrinsically contributes to neuronal dysfunctions and neuronal cell death in polyglutamine (polyQ) diseases. In addition, an expanded polyQ-containing protein in microglia also leads to apoptosis of neurons. However, detailed morphological analy...

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Detalles Bibliográficos
Autores principales: Owada, Ryuji, Awata, Saaya, Suzue, Kazutomo, Kanetaka, Hiroyasu, Kakuta, Yohei, Nakamura, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486442/
https://www.ncbi.nlm.nih.gov/pubmed/32954034
http://dx.doi.org/10.1016/j.heliyon.2020.e04851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486442/
https://www.ncbi.nlm.nih.gov/pubmed/32954034
http://dx.doi.org/10.1016/j.heliyon.2020.e04851

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