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Polyglutamine-containing microglia leads to disturbed differentiation and neurite retraction of neuron-like cells
Expanded polyglutamine-containing proteins in neurons intrinsically contributes to neuronal dysfunctions and neuronal cell death in polyglutamine (polyQ) diseases. In addition, an expanded polyQ-containing protein in microglia also leads to apoptosis of neurons. However, detailed morphological analy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486442/ https://www.ncbi.nlm.nih.gov/pubmed/32954034 http://dx.doi.org/10.1016/j.heliyon.2020.e04851 |