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In situ apolipoprotein E-enriched corona guides dihydroartemisinin-decorating nanoparticles towards LDLr-mediated tumor-homing chemotherapy

The therapeutic efficiency of active targeting nanoparticulate drug delivery systems (nano-DDS) is highly compromised by the plasma proteins adsorption on nanoparticles (NPs) surface, which significantly hinders cell membrane receptors to recognize the designed ligands, and provokes the off-target t...

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Detalles Bibliográficos
Autores principales: Li, Zhenbao, Zhu, Jiaojiao, Wang, Yongqi, Zhou, Mei, Li, Dan, Zheng, Shunzhe, Yin, LiLi, Luo, Cong, Zhang, Huicong, Zhong, Lu, Li, Wei, Wang, Jian, Gui, Shuangying, Cai, Biao, Wang, Yongjun, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486546/
https://www.ncbi.nlm.nih.gov/pubmed/32952671
http://dx.doi.org/10.1016/j.ajps.2019.05.002