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Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation

Resveratrol (RES), a non-flavonoid polyphenol extracted from a wide variety of plants, exhibits neuroprotective activities against Parkinson's disease (PD). However, undesirable water solubility of RES reduces its oral bioavailability and demonstrates low efficacy in blood and brain, thus limit...

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Detalles Bibliográficos
Autores principales: Xiong, Sha, Liu, Wei, Zhou, Yile, Mo, Yousheng, Liu, Yao, Chen, Xiaojia, Pan, Huafeng, Yuan, Dongsheng, Wang, Qi, Chen, Tongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486547/
https://www.ncbi.nlm.nih.gov/pubmed/32952674
http://dx.doi.org/10.1016/j.ajps.2019.04.003