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Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation
Resveratrol (RES), a non-flavonoid polyphenol extracted from a wide variety of plants, exhibits neuroprotective activities against Parkinson's disease (PD). However, undesirable water solubility of RES reduces its oral bioavailability and demonstrates low efficacy in blood and brain, thus limit...
Autores principales: | Xiong, Sha, Liu, Wei, Zhou, Yile, Mo, Yousheng, Liu, Yao, Chen, Xiaojia, Pan, Huafeng, Yuan, Dongsheng, Wang, Qi, Chen, Tongkai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486547/ https://www.ncbi.nlm.nih.gov/pubmed/32952674 http://dx.doi.org/10.1016/j.ajps.2019.04.003 |
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