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Let-7 miRNA and CDK4 siRNA co-encapsulated in Herceptin-conjugated liposome for breast cancer stem cells

Recently, breast cancer stem cells (BCSCs) have rapidly emerged as a novel target for the therapy of breast cancer as they play critical roles in tumor growth, maintenance, metastasis, and recurrence. Let-7 miRNA is known to be downregulated in a variety of cancers, especially BCSCs, whereas CDK4 be...

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Detalles Bibliográficos
Autores principales: Shin, Jeong Hyun, Shin, Dae Hwan, Kim, Jin Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486552/
https://www.ncbi.nlm.nih.gov/pubmed/32952670
http://dx.doi.org/10.1016/j.ajps.2019.03.001