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Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin: A biosensor evaluation and interaction study

The bitterness of a drug is a major challenge for patient acceptability and compliance, especially for children. Due to the toxicity of medication, a human taste panel test has certain limitations. Atomoxetine hydrochloride (HCl), which is used for the treatment of attention deficit/hyperactivity di...

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Detalles Bibliográficos
Autores principales: Li, Shuying, Zhang, Ying, Khan, Abdur Rauf, He, Shuwang, Wang, Yingxin, Xu, Jiangkang, Zhai, Guangxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486553/
https://www.ncbi.nlm.nih.gov/pubmed/32952672
http://dx.doi.org/10.1016/j.ajps.2019.11.001