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α-Synuclein Induces Progressive Changes in Brain Microstructure and Sensory-Evoked Brain Function That Precedes Locomotor Decline

In vivo functional and structural brain imaging of synucleinopathies in humans have provided a rich new understanding of the affected networks across the cortex and subcortex. Despite this progress, the temporal relationship between α-synuclein (α-syn) pathology and the functional and structural cha...

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Detalles Bibliográficos
Autores principales: Chu, Winston T., DeSimone, Jesse C., Riffe, Cara J., Liu, Han, Chakrabarty, Paramita, Giasson, Benoit I., Vedam-Mai, Vinata, Vaillancourt, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486650/
https://www.ncbi.nlm.nih.gov/pubmed/32669353
http://dx.doi.org/10.1523/JNEUROSCI.0189-20.2020