Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations

Following advancements in the field of genotoxicology, it has become widely accepted that 3D models are not only more physiologically relevant but also have the capacity to elucidate more complex biological processes that standard 2D monocultures are unable to. Whilst 3D liver models have been devel...

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Detalles Bibliográficos
Autores principales: Conway, Gillian E, Shah, Ume-Kulsoom, Llewellyn, Samantha, Cervena, Tereza, Evans, Stephen J, Al Ali, Abdullah S, Jenkins, Gareth J, Clift, Martin J D, Doak, Shareen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486679/
https://www.ncbi.nlm.nih.gov/pubmed/32780103
http://dx.doi.org/10.1093/mutage/geaa018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486679/
https://www.ncbi.nlm.nih.gov/pubmed/32780103
http://dx.doi.org/10.1093/mutage/geaa018

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