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Down syndrome iPSC model: endothelial perspective on tumor development

Trisomy 21 (T21), known as Down syndrome (DS), is a widely studied chromosomal abnormality. Previous studies have shown that DS individuals have a unique cancer profile. While exhibiting low solid tumor prevalence, DS patients are at risk for hematologic cancers, such as acute megakaryocytic leukemi...

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Detalles Bibliográficos
Autores principales: Perepitchka, Mariana, Galat, Yekaterina, Beletsky, Igor P., Iannaccone, Philip M., Galat, Vasiliy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486695/
https://www.ncbi.nlm.nih.gov/pubmed/32934781
http://dx.doi.org/10.18632/oncotarget.27712