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Down syndrome iPSC model: endothelial perspective on tumor development
Trisomy 21 (T21), known as Down syndrome (DS), is a widely studied chromosomal abnormality. Previous studies have shown that DS individuals have a unique cancer profile. While exhibiting low solid tumor prevalence, DS patients are at risk for hematologic cancers, such as acute megakaryocytic leukemi...
Autores principales: | Perepitchka, Mariana, Galat, Yekaterina, Beletsky, Igor P., Iannaccone, Philip M., Galat, Vasiliy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486695/ https://www.ncbi.nlm.nih.gov/pubmed/32934781 http://dx.doi.org/10.18632/oncotarget.27712 |
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