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Target search and recognition mechanisms of glycosylase AlkD revealed by scanning FRET-FCS and Markov state models
DNA glycosylase is responsible for repairing DNA damage to maintain the genome stability and integrity. However, how glycosylase can efficiently and accurately recognize DNA lesions across the enormous DNA genome remains elusive. It has been hypothesized that glycosylase translocates along the DNA b...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486748/ https://www.ncbi.nlm.nih.gov/pubmed/32820079 http://dx.doi.org/10.1073/pnas.2002971117 |