IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome

Cytokine release syndrome (CRS) is a life-threatening complication induced by systemic inflammatory responses to infections, including bacteria and chimeric antigen receptor T cell therapy. There are currently no immunotherapies with proven clinical efficacy and understanding of the molecular mechan...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Sujin, Tanaka, Toshio, Inoue, Hitomi, Ono, Chikako, Hashimoto, Shoji, Kioi, Yoshiyuki, Matsumoto, Hisatake, Matsuura, Hiroshi, Matsubara, Tsunehiro, Shimizu, Kentaro, Ogura, Hiroshi, Matsuura, Yoshiharu, Kishimoto, Tadamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486751/
https://www.ncbi.nlm.nih.gov/pubmed/32826331
http://dx.doi.org/10.1073/pnas.2010229117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486751/
https://www.ncbi.nlm.nih.gov/pubmed/32826331
http://dx.doi.org/10.1073/pnas.2010229117

Ejemplares similares