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Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression

Stress-induced disturbances of brain homeostasis and neuroinflammation have been implicated in the pathophysiology of mood disorders. In major depressive disorder (MDD), elevated levels of proinflammatory cytokines and chemokines can be found in peripheral blood, but very little is known about the c...

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Detalles Bibliográficos
Autores principales: Böttcher, Chotima, Fernández-Zapata, Camila, Snijders, Gijsje J. L., Schlickeiser, Stephan, Sneeboer, Marjolein A. M., Kunkel, Desiree, De Witte, Lot D., Priller, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486938/
https://www.ncbi.nlm.nih.gov/pubmed/32917850
http://dx.doi.org/10.1038/s41398-020-00992-2