Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging

Early therapeutic interventions are essential to prevent Alzheimer Disease (AD). The association of several inflammation-related genetic markers with AD and the early activation of pro-inflammatory pathways in AD suggest inflammation as a plausible therapeutic target. Inflammatory Caspase-1 has a si...

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Detalles Bibliográficos
Autores principales: Flores, Joseph, Noël, Anastasia, Foveau, Bénédicte, Beauchet, Olivier, LeBlanc, Andréa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486940/
https://www.ncbi.nlm.nih.gov/pubmed/32917871
http://dx.doi.org/10.1038/s41467-020-18405-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486940/
https://www.ncbi.nlm.nih.gov/pubmed/32917871
http://dx.doi.org/10.1038/s41467-020-18405-9

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