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Hepatic lipids promote liver metastasis

Obesity predisposes to cancer and a virtual universality of nonalcoholic fatty liver disease (NAFLD). However, the impact of hepatic steatosis on liver metastasis is enigmatic. We find that while control mice were relatively resistant to hepatic metastasis, those which were lipodystrophic or obese,...

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Detalles Bibliográficos
Autores principales: Li, Yongjia, Su, Xinming, Rohatgi, Nidhi, Zhang, Yan, Brestoff, Jonathan R., Shoghi, Kooresh I., Xu, Yalin, Semenkovich, Clay F., Harris, Charles A., Peterson, Lindsay L., Weilbaecher, Katherine N., Teitelbaum, Steven L., Zou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487169/
https://www.ncbi.nlm.nih.gov/pubmed/32879136
http://dx.doi.org/10.1172/jci.insight.136215