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N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression

BACKGROUND/AIMS: N-acetylcysteine (NAC) affects signaling pathways involved in apoptosis, angiogenesis, cell growth and arrest, redox-regulated gene expression, and the inflammatory response. However, it is not known how the signal mechanism for tight junctional protein claudin (CLDN) 18 is regulate...

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Detalles Bibliográficos
Autores principales: Lee, Pureun-Haneul, Hong, Jisu, Jang, An-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487305/
https://www.ncbi.nlm.nih.gov/pubmed/32098455
http://dx.doi.org/10.3904/kjim.2019.105