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Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage

Aminoglycoside-induced hair cell (HC) loss is one of the most important causes of hearing loss. After entering the inner ear, aminoglycosides induce the production of high levels of reactive oxygen species (ROS) that subsequently activate apoptosis in HCs. Citicoline, a nucleoside derivative, plays...

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Detalles Bibliográficos
Autores principales: Zhong, Zhenhua, Fu, Xiaolong, Li, He, Chen, Jie, Wang, Maohua, Gao, Song, Zhang, Liyan, Cheng, Cheng, Zhang, Yuan, Li, Peipei, Zhang, Shasha, Qian, Xiaoyun, Shu, Yilai, Chai, Renjie, Gao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487320/
https://www.ncbi.nlm.nih.gov/pubmed/32984303
http://dx.doi.org/10.3389/fcell.2020.00712