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Construction of polycistronic baculovirus surface display vectors to express the PCV2 Cap(d41) protein and analysis of its immunogenicity in mice and swine

To increase expression levels of the PCV2 Cap(d41) protein, novel baculovirus surface display vectors with multiple expression cassettes were constructed to create recombinant baculoviruses BacSC-Cap(d41), BacDD-2Cap(d41), BacDD-3Cap(d41), and BacDD-4Cap(d41). Our results reveal that the recombinant...

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Detalles Bibliográficos
Autores principales: Chen, Ya-Yi, Yang, Wei-Chen, Chang, Yu-Kang, Wang, Chi-Young, Huang, Wei-Ru, Li, Jyun-Yi, Chuang, Kuo-Pin, Wu, Hung-Yi, Chang, Ching-Dong, Nielsen, Brent L., Liu, Hung-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487469/
https://www.ncbi.nlm.nih.gov/pubmed/32907618
http://dx.doi.org/10.1186/s13567-020-00836-3